SCHEMBL2991550

SCHEMBL2991550

CCC1(C2(C3CCCCC3)CCCCC2)CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.32
ABCB11 O95342 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
CHRM3 P20309 1/20 0.32
DRD1 P21728 1/20 0.32
HRH2 P25021 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SCN1A P35498 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2993606 1.00 CYP3A4 (0.32) CYP3A4ABCB11LMNACYP1A2CHRM2
SCHEMBL3003504 0.83 CYP1A2 (0.30) CYP3A4ABCB11LMNACYP1A2CHRM2
SCHEMBL2998646 0.83 CYP1A2 (0.30) CYP3A4ABCB11LMNACYP1A2CHRM2
SCHEMBL2994633 0.80 CYP1A2 (0.36) CYP1A2
SCHEMBL2991472 0.80 CYP1A2 (0.36) CYP1A2
SCHEMBL5409875 0.75 LMNA (0.32) LMNATSHRHSD17B10
SCHEMBL7016412 0.73 LMNA (0.31) LMNATSHR
SCHEMBL9463108 0.73 LMNA (0.31) LMNATSHR
SCHEMBL2679027 0.73 HSD17B10 (0.33) LMNATSHRHSD17B10
SCHEMBL8964788 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
EP-0362673-B1 1,1-DICYCLOHEXYL CYCLOALKANE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF AND TRACTION-DRIVE FLUID CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-07-28 EP disclosed
US-5107041-A 1,1-DICYCLOHEXYL CYCLOALKANE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF AND TRACTION-DRIVE FLUID CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 1992-04-21 US disclosed
EP-0362673-A1 1,1-dicyclohexyl cycloalkane derivative, method for the preparation thereof and traction-drive fluid containing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-04-11 EP disclosed