SCHEMBL29915716

SCHEMBL29915716

Cc1cc(C=O)cc[n+]1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.39
ALDH1A1 P00352 10/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A3 P47895 2/20 0.34
AOX1 Q06278 1/20 0.33
TRIM24 O15164 1/20 0.33
HPGD P15428 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
FDPS P14324 1/20 0.32
UNG P13051 1/20 0.31
TYR P14679 1/20 0.31
CYP2A13 Q16696 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1426656 1.00 CYP2A6 (0.39) CYP2A6ALDH1A1TSHRKDM4EPTGS2
SCHEMBL4829147 0.82 CHAT (0.44) ALDH1A1TSHRKDM4ERAB9AHDAC8
SCHEMBL12161660 0.78 KDM4E (0.40) CYP2A6ALDH1A1TSHRKDM4EPTGS2
SCHEMBL4829142 0.77
SCHEMBL305827 0.77 CYP2A6 (0.38) CYP2A6ALDH1A1TSHRKDM4EPTGS2
SCHEMBL6033654 0.69 QDPR (0.37) KDM4ETDP1
SCHEMBL2297527 0.69
SCHEMBL1425978 0.69
Iodide SCHEMBL989753 0.67 ACHE (0.35) CYP2A6KDM4ETDP1
Iodide SCHEMBL7049251 0.67 HDAC8 (0.54) CYP2A6ALDH1A1KDM4ERAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN disclosed