Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636716 | 0.84 | SLC16A3 (0.64) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30878098 | 0.82 | SLC16A3 (0.64) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13944778 | 0.81 | SLC16A3 (0.56) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9771949 | 0.73 | MEN1 (0.74) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2911594 | 0.73 | MAOB (0.80) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1291001 | 0.73 | GPR55 (0.64) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2030497 | 0.73 | SLC16A3 (0.81) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13067106 | 0.73 | CYP19A1 (0.75) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL25490357 | 0.72 | SLC16A3 (0.66) | SLC16A3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13041713 | 0.72 | CYP19A1 (0.69) | SLC16A3MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8366935-B2 | Phyllanthus extract | PHYTRIX INC. | 2013-02-05 | — | — | US | disclosed |
| US-20100190726-A1 | Novel Phyllanthus Extract | PHYTRIX JV, LLC (US) | 2010-07-29 | — | — | US | disclosed |
| EP-2116253-A1 | Novel phyllanthus extract | Phytrix JV, LLC (US) | 2009-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190726-A1 | Novel Phyllanthus Extract | LRPPRC, PRLHR, PRRC2C | SLC16A3 3450/4885MEN1 3427/4885KMT2A 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.