Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944778 | 0.85 | SLC16A3 (0.56) | SLC16A3ALDH1A1HPGDKDM4ESLC16A1 | |
| SCHEMBL2991615 | 0.84 | SLC16A3 (0.55) | SLC16A3ALDH1A1HPGDKDM4ESLC16A1 | |
| SCHEMBL30878098 | 0.84 | SLC16A3 (0.64) | SLC16A3ALDH1A1HPGDKDM4ESLC16A1 | |
| SCHEMBL11128154 | 0.81 | NPC1 (0.55) | ALDH1A1SMN1; SMN2ALOX15KMT2AMEN1 | |
| SCHEMBL2274941 | 0.80 | POLB (0.57) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL30002655 | 0.80 | POLB (0.57) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL1291001 | 0.80 | GPR55 (0.64) | SLC16A3ALDH1A1HPGDKDM4ESLC16A1 | |
| SCHEMBL839032 | 0.78 | SLC16A3 (1.00) | SLC16A3ALDH1A1HPGDKDM4ESLC16A1 | |
| SCHEMBL21121524 | 0.78 | GPR55 (0.66) | SLC16A3ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10845026 | 0.77 | CA12 (0.50) | SLC16A3KDM4EKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |