Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086811 | 1.00 | KMT2A (0.48) | KMT2AMAPK1LTA4HGRM5CASP3 | |
| SCHEMBL25152984 | 1.00 | KMT2A (0.48) | KMT2AMAPK1LTA4HGRM5CASP3 | |
| SCHEMBL29919559 | 0.83 | MAPK1 (0.41) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL25152978 | 0.83 | MAPK1 (0.41) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL27086725 | 0.83 | MAPK1 (0.41) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL27086721 | 0.82 | MAPK1 (0.62) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL25152979 | 0.82 | MAPK1 (0.62) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL29919552 | 0.82 | MAPK1 (0.62) | KMT2AMAPK1LTA4HGRM5PPARG | |
| SCHEMBL23144183 | 0.78 | MAPK1 (0.67) | KMT2AMAPK1GRM5CASP3RAB9A | |
| SCHEMBL1680623 | 0.77 | CASP3 (0.61) | GRM5CASP3GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320105-A1 | OPIOID RECEPTOR MODULATORS | Epiodyne, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117425644-A | Opioid receptor modulators | 埃皮欧黛公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2022216750-A1 | OPIOID RECEPTOR MODULATORS | EPIODYNE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |