Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25152271 | 1.00 | CTSB (0.42) | CTSBCTSSCTSKATMKDM4E | |
| SCHEMBL29162578 | 1.00 | CTSB (0.42) | CTSBCTSSCTSKATMKDM4E | |
| SCHEMBL29919513 | 0.85 | CTSS (0.49) | CTSBCTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL25152122 | 0.85 | CTSS (0.49) | CTSBCTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL4624438 | 0.85 | PTPN1 (0.54) | CTSBCTSSCTSKPTPN1 | |
| SCHEMBL3317027 | 0.85 | CTSS (0.49) | CTSBCTSSCTSKKDM4EALDH1A1 | |
| SCHEMBL29919588 | 0.83 | CTSB (0.41) | CTSBCTSSCTSKATMKDM4E | |
| SCHEMBL25152326 | 0.83 | CTSB (0.41) | CTSBCTSSCTSKATMKDM4E | |
| SCHEMBL27086858 | 0.83 | CTSB (0.41) | CTSBCTSSCTSKATMKDM4E | |
| SCHEMBL7353984 | 0.81 | CTSS (0.61) | CTSBCTSSCTSKATMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320105-A1 | OPIOID RECEPTOR MODULATORS | Epiodyne, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216750-A1 | OPIOID RECEPTOR MODULATORS | EPIODYNE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |