Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985564 | 1.00 | AR (0.41) | ARF2CFDMAOAMAOB | |
| SCHEMBL4490244 | 0.83 | AR (0.45) | ARF2CFDMAOAMAOB | |
| SCHEMBL1319411 | 0.83 | AR (0.44) | ARF2CFDMAOAMAOB | |
| SCHEMBL31457779 | 0.81 | CREBBP (0.38) | ARMAOAMAOBCREBBPNOS1 | |
| SCHEMBL20704837 | 0.76 | ALDH1A1 (0.46) | MAOASMN1; SMN2ALDH1A1TSHRPPARG | |
| SCHEMBL3981208 | 0.76 | F2 (0.41) | ARF2CFDMAOAMAOB | |
| SCHEMBL4491356 | 0.72 | NOS1 (0.42) | ARF2CFDMAOAMAOB | |
| SCHEMBL14361975 | 0.72 | ALDH1A1 (0.44) | ARMAOAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3498795 | 0.71 | F2 (0.52) | ARF2CFDMAOAMAOB | |
| SCHEMBL1559364 | 0.71 | ABCG2 (0.54) | ARF2CFDMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004861-A | Allosteric EGFR inhibitors and methods of use thereof | 达纳-法伯癌症研究所股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115066240-A | Allosteric EGFR inhibitors and methods of use thereof | 达纳-法伯癌症研究所股份有限公司 | 2022-09-16 | — | — | CN | disclosed |