⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896140 | 0.78 | PDE8B (0.33) | — | |
| SCHEMBL10136430 | 0.78 | — | — | |
| SCHEMBL9207562 | 0.77 | — | — | |
| SCHEMBL14975247 | 0.75 | PIK3CD (0.38) | — | |
| SCHEMBL627733 | 0.75 | PIK3CD (0.38) | — | |
| SCHEMBL16322147 | 0.75 | PIK3CD (0.38) | — | |
| SCHEMBL14478291 | 0.75 | — | — | |
| SCHEMBL8528473 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL6204634 | 0.75 | — | — | |
| SCHEMBL11734254 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319756-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022217276-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-10-13 | — | — | WO | disclosed |