Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20966328 | 1.00 | MEN1 (0.52) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL20945448 | 0.82 | MAPT (0.62) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL20966323 | 0.81 | RAC1 (0.54) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL29920964 | 0.81 | RAC1 (0.54) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL20945445 | 0.73 | MAPT (0.60) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4726955 | 0.72 | PTGDR2 (0.77) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4728886 | 0.72 | PTGER4 (0.67) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL20945432 | 0.71 | MAPT (0.51) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4727906 | 0.71 | PTGER4 (0.67) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL30062001 | 0.71 | PTGER4 (0.67) | MEN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | CDC42, ARHGEF2, HRAS | MEN1 1521/4885MAPT 3790/4885KMT2A 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.