SCHEMBL2992041

SCHEMBL2992041

FC(F)(F)[Zn]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1452996 0.93
Bromide SCHEMBL9810690 0.93
Iodide SCHEMBL11020380 0.93
SCHEMBL6837252 0.72
SCHEMBL5359711 0.68
SCHEMBL668190 0.67
Hydrogen Sulfide SCHEMBL25252062 0.62
SCHEMBL21244130 0.62
SCHEMBL14721708 0.61
SCHEMBL444758 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019219-A Preparation method of perfluoro-2, 4-trimethyl-2-pentene 浙江蓝天环保高科技股份有限公司 2024-11-26 CN disclosed
EP-1661897-B1 PYRROLOPYRIMIDINONE DERIVATIVE TEIJIN PHARMA LTD (JP) 2013-12-04 EP disclosed
US-7786259-B2 Attachment and elaboration strategies for inverse peptide synthesis THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2010-08-31 US disclosed
US-7557113-B2 Substituted pyrrolo[3,2-d]pyrimidine derivatives TEIJIN PHARMA LIMITED (JP) 2009-07-07 US disclosed
US-20080200644-A1 Method for inverse solid phase synthesis of peptides THE CURATORS OF THE UNIVERSITY OF MISSOURI 2008-08-21 US disclosed
US-20080039612-A1 ATTACHMENT AND ELABORATION STRATEGIES FOR INVERSE PEPTIDE SYNTHESIS THE CURATORS OF THE UNIVERSITY OF MISSOURI 2008-02-14 US disclosed
US-7244815-B2 Attachment and elaboration strategies for inverse peptide synthesis THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2007-07-17 US disclosed
US-7214769-B2 Method for inverse solid phase synthesis of peptides THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2007-05-08 US disclosed
US-20060160831-A1 Pyrrolopyrimidinone derivatives TEIJIN PHARMA LIMITED (JP) 2006-07-20 US disclosed
EP-1661897-A1 PYRROLOPYRIMIDINONE DERIVATIVE Teijin Pharma Limited (JP) 2006-05-31 EP disclosed
EP-0574839-B1 Process for the preparation of difluormethylethers and esters SOLVAY FLUOR & DERIVATE (DE) 1996-10-09 EP disclosed
US-5455371-A Method of producing difluoromethyl ethers and esters and ethers and esters produced thereby SOLVAY FLUOR UND DERIVATIVE GMBH (DE) 1995-10-03 US disclosed
EP-0574839-A2 Process for the preparation of difluormethylethers and esters Solvay Fluor und Derivate GmbH (DE) 1993-12-22 EP disclosed
CN-1063104-A Trifluoromethyl 1-carbon (1-desulfuration) cephem LILLY CO ELI (US) 1992-07-29 CN disclosed
EP-0494733-A1 Trifluoromethyl 1-carba(1-dethia)cephems ELI LILLY AND COMPANY (US) 1992-07-15 EP disclosed
US-5099015-A Antibiotics formed by bromination of trifluoromethanesulfonyl containing cephalosporins ELI LILLY AND COMPANY (US) 1992-03-24 US disclosed
US-4895991-A FROM AROMATIC HALIDE, DIFLUORODIHALOMETHANE, COPPER, CHAIN EXTENSION SUPPRESSING HALIDE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1990-01-23 US disclosed
US-4749802-A REACTING COPPER WITH A DIFLUORODIHALOMETHANE UNIVERSITY OF IOWA RESEARCH FOUNDATION, INC. (US) 1988-06-07 US disclosed
US-4650887-A TRIFLUOROMETHYLCOPPER REAGENT UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1987-03-17 US disclosed
US-4582921-A REACTING DIFLUORIDIHALOMETHANE WITH CADIUM OR ZINC IN APROTIC SOLVENT UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1986-04-15 US disclosed