Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 12/20 | 0.50 |
| ▸ | MAOB | P27338 | 12/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474235 | 0.85 | FTO (0.47) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL3681299 | 0.82 | FTO (0.61) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL31533388 | 0.79 | FTO (0.42) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL17708837 | 0.78 | FTO (0.61) | FTOMAOAMAOBKDM4EGRM5 | |
| SCHEMBL1094182 | 0.78 | MAOA (0.59) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL9432877 | 0.77 | FTO (0.55) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL11036797 | 0.75 | PTPN1 (0.58) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL29621714 | 0.75 | PTPN1 (0.58) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL4951315 | 0.75 | FTO (0.53) | FTOMAOAMAOBKDM4EACHE | |
| SCHEMBL31292049 | 0.75 | FTO (0.53) | FTOMAOAMAOBKDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |