Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20966336 | 1.00 | RAC1 (0.55) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL29920671 | 0.86 | RAC1 (0.59) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL20966311 | 0.86 | RAC1 (0.59) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL20966330 | 0.80 | RAC1 (0.67) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL20945473 | 0.78 | RAC1 (0.69) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL15064233 | 0.77 | RAC1 (0.57) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL20945449 | 0.77 | NTRK1 (0.53) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL20945431 | 0.76 | PDE10A (0.41) | MAPTKDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL20945474 | 0.75 | RAC1 (0.63) | RAC1MAPTKDM4EHPGDLMNA | |
| SCHEMBL25186625 | 0.74 | MAPT (0.66) | MAPTKDM4EHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | CDC42, ARHGEF2, HRAS | RAC1 7/4885MAPT 3790/4885KDM4E 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.