Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920644 | 1.00 | RORC (0.35) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920356 | 0.78 | AKR1B1 (0.46) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920345 | 0.78 | AKR1B1 (0.37) | RORC | |
| SCHEMBL29920828 | 0.76 | CA12 (0.36) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920997 | 0.76 | CA12 (0.36) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920701 | 0.74 | CA12 (0.35) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920439 | 0.74 | AKR1B1 (0.48) | RORC | |
| SCHEMBL29920339 | 0.74 | CA12 (0.35) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920680 | 0.72 | AKR1B1 (0.37) | RORCCA12CA1CA7CA14 | |
| SCHEMBL29920342 | 0.71 | AKR1B1 (0.36) | RORCCA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |