Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 14/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920339 | 1.00 | CA12 (0.35) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920828 | 0.96 | CA12 (0.36) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920997 | 0.96 | CA12 (0.36) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920356 | 0.88 | AKR1B1 (0.46) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920439 | 0.78 | AKR1B1 (0.48) | AKR1B1RORC | |
| SCHEMBL29920830 | 0.76 | AKR1B1 (0.43) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920666 | 0.74 | RORC (0.35) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920644 | 0.74 | RORC (0.35) | CA12CA1CA7CA14RORC | |
| SCHEMBL29920385 | 0.72 | MAP3K14 (0.39) | CA12CA1CA7CA14AKR1B1 | |
| SCHEMBL29920603 | 0.71 | MAP3K14 (0.38) | CA12CA1CA7CA14AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |