Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745341 | 0.98 | CNR1 (0.51) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| SCHEMBL11599714 | 0.98 | CNR1 (0.51) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| SCHEMBL9745331 | 0.98 | CNR1 (0.51) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| SCHEMBL11683157 | 0.98 | CNR1 (0.51) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| SCHEMBL11599964 | 0.98 | CNR1 (0.51) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL29058210 | 0.96 | CNR1 (0.50) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL28158327 | 0.96 | CNR1 (0.50) | CNR2CNR1ALDH1A1KDM4ETSHR | |
| SCHEMBL2450671 | 0.93 | — | — | |
| SCHEMBL27415714 | 0.87 | ALDH1A1 (0.58) | CNR2CNR1ALDH1A1KDM4EKCNK3 | |
| SCHEMBL25554197 | 0.86 | ALDH1A1 (0.50) | CNR2CNR1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765865-B1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU KOGYO CO LTD (JP) | 2001-12-12 | — | — | EP | claimed |
| EP-0720852-B1 | REMEDY FOR NERVOUS DISEASES | SEIKAGAKU KOGYO CO LTD (JP) | 2000-11-22 | — | — | EP | claimed |
| US-5849326-A | Method for treating neuronal diseases via administration of 2-acylaminopropanol derivatives | SEIKAGAKU CORPORATION (JP) | 1998-12-15 | — | — | US | claimed |
| US-5763438-A | ANTIVIRAL AGENTS | SEIKAGAKU CORPORATION (JP) | 1998-06-09 | — | — | US | claimed |
| US-5707649-A | USING A 2-ACYLAMINOPROPANOL DERIVATIVE | SEIKAGAKU CORPORATION (JP) | 1998-01-13 | — | — | US | claimed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | claimed |
| EP-0720852-A1 | REMEDY FOR NERVOUS DISEASES | SEIKAGAKU CORPORATION (JP) | 1996-07-10 | — | — | EP | claimed |
| JP-9169664-A | — | — | None | — | — | JP | disclosed |
| EP-2594565-B1 | 2-acylaminopropanol-type glucosylceramide synthase inhibitors | GENZYME CORP (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-2594563-B1 | 2-acylaminopropanol-type glucosylceramide synthase inhibitors | GENZYME CORP (US) | 2018-07-18 | — | — | EP | disclosed |
| EP-2594563-B1 | 2-acylaminopropanol-type glucosylceramide synthase inhibitors | GENZYME CORP (US) | 2018-07-18 | — | — | EP | disclosed |
| EP-2594564-B1 | 2-acylaminopropanol-type glucosylceramide synthase inhibitors | GENZYME CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2594562-B1 | 2-acylaminopropanol-type glucosylceramide synthase inhibitors | GENZYME CORP (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | disclosed |
| CN-1128951-A | Remedy for nervous diseases | SEIKAGAKU KOGYO CO LTD (JP) | 1996-08-14 | — | — | CN | disclosed |
| EP-0720852-A1 | REMEDY FOR NERVOUS DISEASES | SEIKAGAKU CORPORATION (JP) | 1996-07-10 | — | — | EP | disclosed |
| EP-0720852-A1 | REMEDY FOR NERVOUS DISEASES | SEIKAGAKU CORPORATION (JP) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995034530-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995005177-A1 | REMEDY FOR NERVOUS DISEASES | SEIKAGAKU CORPORATION (JP) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994027607-A1 | ANTIVIRAL AGENT | SEIKAGAKU CORPORATION (JP) | 1994-12-08 | — | — | WO | disclosed |