Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | ADH1B | P00325 | 2/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | ADH7 | P40394 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745341 | 0.88 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL11683157 | 0.88 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL9745331 | 0.88 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL11599964 | 0.88 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL11599714 | 0.88 | CNR1 (0.51) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL28158327 | 0.86 | CNR1 (0.50) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL29058210 | 0.86 | CNR1 (0.50) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL299216 | 0.86 | CNR2 (0.49) | ALDH1A1TSHRCNR1CNR2KDM4E | |
| SCHEMBL26364841 | 0.83 | LMNA (0.40) | TSHRCNR1KDM4ELMNA | |
| SCHEMBL24725721 | 0.79 | TSHR (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159532-A1 | PARATHYROID HORMONE (PTH) RECEPTOR ANTAGONISTS AND USES THEREOF | PTH1R, CALCR, VDR | ALDH1A1 4312/4885TSHR 13/4885CNR1 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.