Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2594793 | 1.00 | S100A4 (0.43) | S100A4PTPRCMETAP1KDM4EHTT | |
| SCHEMBL5329304 | 0.84 | S100A4 (0.43) | S100A4PTPRCMETAP1BCL2MCL1 | |
| SCHEMBL13135 | 0.81 | KDM4E (0.58) | S100A4PTPRCMETAP1KDM4EHTT | |
| SCHEMBL5956746 | 0.78 | KDM4E (0.47) | S100A4PTPRCMETAP1KDM4EHTT | |
| SCHEMBL6812146 | 0.76 | HTT (0.41) | KDM4EHTTCA1CA2CA7 | |
| SCHEMBL9159671 | 0.76 | VHL (0.49) | S100A4METAP1KDM4EHTTCA1 | |
| SCHEMBL13539308 | 0.76 | KDM4E (0.38) | KDM4EHTTMAOAMAOB | |
| SCHEMBL13871409 | 0.76 | EPHX2 (0.53) | METAP1KDM4EHTTCA1CA2 | |
| SCHEMBL31040913 | 0.73 | TDP2 (0.42) | KDM4EHTTCA1CA2CA4 | |
| SCHEMBL11877796 | 0.72 | MEN1 (0.46) | KDM4EHTTPARP10TDP2PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |