Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922061 | 0.92 | POLB (0.35) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL21013530 | 0.75 | POLB (0.46) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL29606664 | 0.75 | POLB (0.46) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30504137 | 0.74 | POLB (0.45) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL29922012 | 0.71 | POLB (0.42) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL6741228 | 0.70 | MEN1 (0.50) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL29921913 | 0.69 | POLB (0.41) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL6742481 | 0.67 | MEN1 (0.54) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL12969896 | 0.65 | SMN1; SMN2 (0.45) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29922416 | 0.65 | POLB (0.40) | POLBMEN1KMT2AFTOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |