Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606664 | 0.84 | POLB (0.46) | POLBPDK2MEN1KMT2AFTO | |
| SCHEMBL21013530 | 0.84 | POLB (0.46) | POLBPDK2MEN1KMT2AFTO | |
| Hydrochloric Acid SCHEMBL30504137 | 0.82 | POLB (0.45) | POLBPDK2MEN1KMT2AFTO | |
| SCHEMBL31073015 | 0.79 | OPRM1 (0.47) | PDK2ALDH1A1TP53LMNAMAPT | |
| SCHEMBL7697104 | 0.76 | CFTR (0.50) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL6742481 | 0.75 | MEN1 (0.54) | POLBPDK2MEN1KMT2AFTO | |
| SCHEMBL1771795 | 0.71 | ALDH1A1 (0.42) | POLBPDK2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29922159 | 0.71 | POLB (0.39) | POLBPDK2MEN1KMT2AFTO | |
| SCHEMBL1814585 | 0.70 | ALDH1A1 (0.40) | POLBMEN1KMT2AFTOSMN1; SMN2 | |
| SCHEMBL11826152 | 0.69 | MEN1 (0.48) | POLBPDK2MEN1KMT2AFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |