Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396451 | 1.00 | BACE1 (0.65) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL7164883 | 0.93 | BACE1 (0.56) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL7169755 | 0.88 | BACE1 (0.51) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL11019341 | 0.84 | MAPT (0.55) | BACE1HSD17B10KDM4EHPGDHDAC1 | |
| SCHEMBL3884069 | 0.84 | ADRA2C (0.64) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL95038 | 0.84 | MAPT (0.55) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL9134263 | 0.84 | HDAC1 (0.49) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL17177679 | 0.84 | MEN1 (0.68) | BACE1HSD17B10KDM4EHPGDHDAC1 | |
| SCHEMBL30894547 | 0.84 | ADRA2C (0.64) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL4571036 | 0.84 | HSD17B10 (0.71) | BACE1HSD17B10KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164859-B | Preparation method of di-amine and polyamine of diphenyl methane series | 万华化学集团股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118164859-A | Preparation method of di-amine and polyamine of diphenyl methane series | 万华化学集团股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117510342-A | Process for the preparation of diamines and polyamines of the diphenylmethane series with improved 2,4-MDA selectivity | 万华化学集团股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117466925-A | Boron-nitrogen doped conjugated polycyclic aromatic hydrocarbon compound and synthetic method and application thereof | 山东大学深圳研究院 | 2024-01-30 | — | — | CN | disclosed |
| CN-110603273-B | Modified block copolymer, method for producing modified block copolymer, and resin composition | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |