Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922357 | 1.00 | BACE1 (0.65) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL7164883 | 0.93 | BACE1 (0.56) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL7169755 | 0.88 | BACE1 (0.51) | BACE1HSD17B10KDM4EHPGDTSHR | |
| SCHEMBL11019341 | 0.84 | MAPT (0.55) | BACE1HSD17B10KDM4EHPGDHDAC1 | |
| SCHEMBL3884069 | 0.84 | ADRA2C (0.64) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL95038 | 0.84 | MAPT (0.55) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL9134263 | 0.84 | HDAC1 (0.49) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL17177679 | 0.84 | MEN1 (0.68) | BACE1HSD17B10KDM4EHPGDHDAC1 | |
| SCHEMBL30894547 | 0.84 | ADRA2C (0.64) | BACE1KDM4EHDAC1HDAC3HDAC2 | |
| SCHEMBL4571036 | 0.84 | HSD17B10 (0.71) | BACE1HSD17B10KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909096-A | Synthesis method of benzimidazole compound mediated by ammonium acetate | 衡阳师范学院 | 2020-11-10 | — | — | CN | claimed |
| EP-2268713-B1 | PROCESS FOR MAKING POLYAMINOPOLYPHENYL METHANES USING A MIXED SOLID ACID CATALYST SYSTEM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-02-21 | — | — | EP | claimed |
| US-20260103446-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2026-04-16 | — | — | US | disclosed |
| EP-4019501-B1 | CFTR REGULATORS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2026-02-04 | — | — | EP | disclosed |
| US-12503447-B2 | CFTR regulators and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-23 | — | — | US | disclosed |
| US-12391654-B2 | CFTR regulators and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-08-19 | — | — | US | disclosed |
| WO-2025073928-A1 | PROCESS FOR PREPARING MDA | BASF SE (DE) | 2025-04-10 | — | — | WO | disclosed |
| US-20250109113-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-04-03 | — | — | US | disclosed |
| EP-3623398-B1 | RESIN COMPOSITION COMPRISING A MODIFIED BLOCK COPOLYMER AND METHOD FOR PRODUCING MODIFIED BLOCK COPOLYMER | ASAHI CHEMICAL IND (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-12065412-B2 | CFTR regulators and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-08-20 | — | — | US | disclosed |
| EP-4071140-B1 | CFTR REGULATORS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2024-07-03 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |
| US-4147724-A | Process for the preparation of polyamines | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-03 | — | — | US | disclosed |
| US-4104194-A | 1,2-FUSED 5- OR 6-MEMBERED 1,3-DINITROGEN HETEROCYCLIC COMPOUNDS AS ANTICORROSION AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4087459-A | Process for the preparation of polyamines | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | disclosed |
| US-4048174-A | ANTI-CORROSION AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065412-B2 | CFTR regulators and methods of use thereof | CFTR, SLC26A4, CLCN2 | BACE1 2273/4885HSD17B10 2372/4885KDM4E 4709/4885 |
| US-12391654-B2 | CFTR regulators and methods of use thereof | CFTR, SLC26A4, CLCN2 | BACE1 2273/4885HSD17B10 2372/4885KDM4E 4709/4885 |
| US-20260103446-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | CFTR, CLCN2, SLC26A3 | BACE1 3051/4885HSD17B10 3094/4885KDM4E 4660/4885 |
| US-12503447-B2 | CFTR regulators and methods of use thereof | CFTR, SLC26A4, CLCN2 | BACE1 2273/4885HSD17B10 2372/4885KDM4E 4709/4885 |
| US-20250109113-A1 | CFTR REGULATORS AND METHODS OF USE THEREOF | CFTR, SLC26A4, CLCN2 | BACE1 2273/4885HSD17B10 2372/4885KDM4E 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.