Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362546 | 1.00 | SYK (0.43) | SYKSTAT3ABCG2KDM4EKMT2A | |
| SCHEMBL28362756 | 0.87 | ABCB1 (0.45) | SYKABCG2KDM4EKMT2AMAPT | |
| SCHEMBL29551921 | 0.87 | ABCB1 (0.45) | SYKABCG2KDM4EKMT2AMAPT | |
| SCHEMBL29922810 | 0.87 | ABCB1 (0.45) | SYKABCG2KDM4EKMT2AMAPT | |
| SCHEMBL28359014 | 0.85 | SYK (0.41) | SYKKDM4EKMT2AMAPTMITF | |
| SCHEMBL29551791 | 0.85 | SYK (0.41) | SYKKDM4EKMT2AMAPTMITF | |
| SCHEMBL28359228 | 0.84 | SYK (0.40) | SYKKMT2AMAPTCNR1LMNA | |
| SCHEMBL29922815 | 0.84 | SYK (0.40) | SYKKMT2AMAPTMEN1LMNA | |
| SCHEMBL29922807 | 0.84 | SYK (0.40) | SYKKMT2AMAPTCNR1LMNA | |
| SCHEMBL28359212 | 0.84 | SYK (0.40) | SYKKMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |