Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362756 | 1.00 | ABCB1 (0.45) | ABCB1ABCG2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29551921 | 1.00 | ABCB1 (0.45) | ABCB1ABCG2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29552243 | 0.91 | ABCB1 (0.47) | ABCB1ABCG2AKR1C3AKR1C2MAPT | |
| SCHEMBL28362546 | 0.87 | SYK (0.43) | ABCG2LMNAMAPTSYKTP53 | |
| SCHEMBL29922602 | 0.87 | SYK (0.43) | ABCG2LMNAMAPTSYKTP53 | |
| SCHEMBL29922466 | 0.82 | ABCB1 (0.41) | ABCB1ABCG2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28358863 | 0.82 | ABCB1 (0.41) | ABCB1ABCG2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL29552248 | 0.82 | ABCB1 (0.41) | ABCB1ABCG2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL28359212 | 0.79 | SYK (0.40) | LMNAMAPTSYKMAPK1KMT2A | |
| SCHEMBL29922815 | 0.79 | SYK (0.40) | LMNAMAPTSYKMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |