Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343778 | 1.00 | NPSR1 (0.45) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL31280689 | 0.87 | SYK (0.37) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL31214079 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1L3MBTL1KDM4EPKM | |
| SCHEMBL21679164 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL20911423 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL31473635 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL21702310 | 0.83 | NPSR1 (0.43) | NPSR1ALDH1A1L3MBTL1KDM4EPKM | |
| SCHEMBL5886488 | 0.81 | ALDH1A1 (0.44) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL31590096 | 0.81 | ALDH1A1 (0.44) | NPSR1ALDH1A1L3MBTL1SYKKDM4E | |
| SCHEMBL31294112 | 0.81 | ABL1 (0.45) | NPSR1ALDH1A1L3MBTL1SYKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561839-A | Synthesis method of N- (8-oxo-7, 8-dihydropyrido [3,4-c ] pyridazin-3-yl) cyclopropane formamide | 西安石油大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | claimed |
| CN-121991040-A | Preparation method of deuterium-celecoxib | 南通常佑药业科技有限公司 | 2026-05-08 | — | — | CN | disclosed |
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-118440052-B | Compound and application thereof in preparation of TYK2 kinase inhibitor | 四川大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-118561839-A | Synthesis method of N- (8-oxo-7, 8-dihydropyrido [3,4-c ] pyridazin-3-yl) cyclopropane formamide | 西安石油大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118561839-A | Synthesis method of N- (8-oxo-7, 8-dihydropyrido [3,4-c ] pyridazin-3-yl) cyclopropane formamide | 西安石油大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118440052-A | Compound and application thereof in preparation of TYK2 kinase inhibitor | 四川大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-117083268-B | Amino heteroaryl compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| EP-4322954-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | Merck Sharp & Dohme LLC (US) | 2024-02-21 | — | — | EP | disclosed |
| CN-117083268-A | Amino heteroaryl compounds and compositions | 安锐生物医药科技(广州)有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112390787-B | Deuterated piperazine amide compound and preparation method and application thereof | 安炎达医药技术（广州）有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2022221739-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | MERCK SHARP & DOHME CORP. (US) | 2022-10-20 | — | — | WO | disclosed |
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |