SCHEMBL299227

SCHEMBL299227

NC(=O)Cc1ccccc1O

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.68
HSPA5 P11021 1/20 0.52
GAA P10253 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TAAR1 Q96RJ0 1/20 0.50
IDO1 P14902 2/20 0.48
TSHR P16473 2/20 0.46
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA2 P00918 3/20 0.45
CA12 O43570 2/20 0.43
CA9 Q16790 1/20 0.42
MPO P05164 1/20 0.42
KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4655209 1.00 AKR1B1 (0.68) AKR1B1HSPA5GAANPSR1TAAR1
Methane SCHEMBL22289679 0.98 AKR1B1 (0.65) AKR1B1HSPA5GAANPSR1TAAR1
Butane SCHEMBL9614624 0.92 AKR1B1 (0.59) AKR1B1HSPA5GAANPSR1TAAR1
Benzoic Acid SCHEMBL4776756 0.89 AKR1B1 (0.60) AKR1B1HSPA5GAANPSR1TAAR1
SCHEMBL10339218 0.85 AKR1B1 (0.46) AKR1B1GAANPSR1TSHRCYP2D6
Benzene SCHEMBL15265833 0.83 AKR1B1 (0.50) AKR1B1GAANPSR1TSHRCYP2D6
SCHEMBL11029713 0.83 GAA (0.53) AKR1B1GAANPSR1TAAR1ALDH1A1
SCHEMBL10916470 0.82 AKR1B1 (0.68) AKR1B1HSPA5TAAR1IDO1TSHR
SCHEMBL4810865 0.82 AKR1B1 (0.51) AKR1B1GAANPSR1TAAR1CA2
SCHEMBL72309 0.81 AKR1B1 (1.00) AKR1B1HSPA5GAATAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118502207-A Photoresist stripping liquid for semiconductor chip and preparation method and application thereof 浙江奥首材料科技有限公司 2024-08-16 CN claimed
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids CONAGEN INC. (US) 2024-04-02 US claimed
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS CONAGEN INC. (US) 2022-12-22 US claimed
EP-3946317-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL Mestex AG (CH) 2022-02-09 EP claimed
US-20220008384-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL MESTEX AG (CH) 2022-01-13 US claimed
US-20210317485-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS CONAGEN INC. 2021-10-14 US claimed
WO-2020191506-A1 COMPOSITION COMPRISING CAPSAICIN OR A CAPSACINOID FOR POSTOPERATIVE PAIN CONTROL MESTEX AG (CH) 2020-10-01 WO claimed
EP-3621619-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VISCERAL PAIN Arena Pharmaceuticals, Inc. (US) 2020-03-18 EP claimed
US-10576047-B2 Formulations for the treatment of pain Grünenthal GmbH (DE) 2020-03-03 US claimed
US-20190247336-A1 Formulations for the treatment of pain Grünenthal GmbH (DE) 2019-08-15 US claimed
EP-1363906-A2 HETEROCYCLIC INHIBITORS OF ERK2 AND USES THEREOF VERTEX PHARMACEUTICALS INCORPORATED (US) 2003-11-26 EP claimed
WO-2002064586-A2 HETEROCYCLIC INHIBITORS OF ERK2 AND USES THEREOF VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-08-22 WO claimed
US-6197226-B1 COMPRISING DIPPING RESIN INTO A LIQUID CONTAINING POLAR COMPOUND SELECTED FROM POLAR INORGANIC COMPOUNDS AND POLAR ORGANIC COMPOUNDS AND TINTING RESIN, WHEREIN RESIN IS OBTAINED BY CURING BY POLYMERIZATION A SULFUR CONTAINING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY (JP) 2001-03-06 US claimed
EP-0379048-B1 Beta-lactamase assays employing chromogenic precipitating substrates ABBOTT LAB (US) 1995-09-13 EP claimed
WO-1994024095-A1 IMMUNOSUPPRESSIVE AGENTS ABBOTT LABORATORIES (US) 1994-10-27 WO claimed
US-4978613-A Beta-lactamase assay employing chromogenic precipitating substrates ABBOTT LABORATORIES (US) 1990-12-18 US claimed
EP-0379048-A2 Beta-lactamase assays employing chromogenic precipitating substrates ABBOTT LABORATORIES (US) 1990-07-25 EP claimed
EP-0153476-B1 PROCESS FOR THE PREPARATION OF HYDROXYPHENYLACETIC-ACID AMIDES BASF Aktiengesellschaft (DE) 1986-10-15 EP claimed
US-4407815-A AMINO ACID DERIVATIVE ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1983-10-04 US claimed
US-4115646-A Process for preparing 7-aminocephalosporanic acid derivatives BEECHAM GROUP LIMITED (GB) 1978-09-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190247336-A1 Formulations for the treatment of pain OPRL1, TRPV1, OPRK1 AKR1B1 2755/4885HSPA5 535/4885GAA 832/4885
US-10576047-B2 Formulations for the treatment of pain OPRL1, TRPV1, OPRK1 AKR1B1 2755/4885HSPA5 535/4885GAA 832/4885
US-20210317485-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS TRPV1, CYP51A1, NAAA AKR1B1 1326/4885HSPA5 1055/4885GAA 1127/4885
US-20220403427-A1 METHOD FOR THE MICROBIAL PRODUCTION OF SPECIFIC NATURAL CAPSAICINOIDS TRPV1, CYP51A1, NAAA AKR1B1 1326/4885HSPA5 1055/4885GAA 1127/4885
US-11946083-B2 Method for the microbial production of specific natural capsaicinoids TRPV1, CYP51A1, NAAA AKR1B1 1326/4885HSPA5 1055/4885GAA 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.