Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214645 | 1.00 | P2RX7 (0.35) | P2RX7CNR2HTR2CSLC6A4AAK1 | |
| SCHEMBL27231342 | 1.00 | P2RX7 (0.35) | P2RX7CNR2HTR2CSLC6A4AAK1 | |
| SCHEMBL27214613 | 0.91 | CNR2 (0.32) | P2RX7CNR2HTR2CSLC6A4AAK1 | |
| SCHEMBL29923581 | 0.91 | CNR2 (0.32) | P2RX7CNR2HTR2CSLC6A4AAK1 | |
| SCHEMBL29923158 | 0.86 | SCN9A (0.34) | P2RX7CNR2HTR2CSLC6A4AAK1 | |
| SCHEMBL29923235 | 0.85 | KDM4C (0.36) | KDM4C | |
| SCHEMBL27214539 | 0.85 | KDM4C (0.36) | KDM4C | |
| SCHEMBL29923339 | 0.85 | GPR119 (0.37) | KDM4C | |
| SCHEMBL29923145 | 0.85 | GPR119 (0.37) | KDM4C | |
| SCHEMBL29923604 | 0.85 | KCNH2 (0.34) | CNR2HTR2CSLC6A4AAK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217232-A1 | CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |