SCHEMBL29923252

SCHEMBL29923252

CN(C[C@@H]1CCOc2c(-c3cnco3)cccc21)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.38
IMPDH2 P12268 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214548 1.00 GPR119 (0.38) GPR119IMPDH2
SCHEMBL29923313 0.87 GPR119 (0.33) GPR119
SCHEMBL29923339 0.86 GPR119 (0.37) GPR119
SCHEMBL29923145 0.86 GPR119 (0.37) GPR119
SCHEMBL27231219 0.86 BRD4 (0.34) GPR119
SCHEMBL27214554 0.86 BRD4 (0.34) GPR119
SCHEMBL27214590 0.86 BRD4 (0.34) GPR119
SCHEMBL29923604 0.84 KCNH2 (0.34)
SCHEMBL29923582 0.84 GPR119 (0.35) GPR119
SCHEMBL29923257 0.84 ADRA2A (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022217232-A1 CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS SUNOVION PHARMACEUTICALS INC. (US) 2022-10-13 WO disclosed