Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL27633784 | 0.89 | SLC7A5 (0.47) | SLC7A5KMT2AMEN1AKR1C3AKR1B10 | |
| SCHEMBL143766 | 0.82 | ALDH1A1 (0.59) | FABP4KMT2AMEN1AKR1C3AKR1B10 | |
| Bromide SCHEMBL20984528 | 0.80 | FABP4 (0.57) | FABP4KMT2AMEN1AKR1C3AKR1B10 | |
| Hydrochloric Acid SCHEMBL27997789 | 0.80 | FABP4 (0.57) | FABP4KMT2AMEN1AKR1C3AKR1B10 | |
| Hydrochloric Acid SCHEMBL1522753 | 0.80 | FABP4 (0.57) | FABP4KMT2AMEN1AKR1C3AKR1B10 | |
| Toluic Acid SCHEMBL7708419 | 0.80 | SLC7A5 (0.52) | SLC7A5FABP4KMT2AMEN1AKR1C3 | |
| Anthranilic Acid SCHEMBL2255713 | 0.80 | SLC7A5 (0.52) | SLC7A5KMT2ATDP1ALDH1A1MAPT | |
| Valine SCHEMBL8693536 | 0.80 | SLC7A5 (0.52) | SLC7A5KMT2AMEN1CYP1A2CYP2C9 | |
| Valine SCHEMBL7706957 | 0.80 | SLC7A5 (0.56) | SLC7A5KMT2AMEN1LMNACYP1A2 | |
| Acetic Acid SCHEMBL27992671 | 0.79 | FABP4 (0.52) | FABP4KMT2AMEN1AKR1C3AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | SLC7A5 4762/4885FABP4 2559/4885KMT2A 1226/4885 |
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | SLC7A5 4762/4885FABP4 2559/4885KMT2A 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.