Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993766 | 0.93 | ALOX15 (0.56) | MAOBHIF1AALOX15POLBALDH1A1 | |
| SCHEMBL1674346 | 0.86 | ALDH1A1 (0.63) | MAOBHIF1APOLBMAPK1ALDH1A1 | |
| SCHEMBL30074614 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL21531023 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL30074608 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL23293634 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL30074571 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL21531034 | 0.82 | CYP1A2 (0.57) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL30074581 | 0.82 | ALOX15 (0.48) | MAOBALOX15POLBMAPK1ALDH1A1 | |
| SCHEMBL3000781 | 0.82 | MAOB (0.51) | MAOBHIF1AMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-29 | — | — | US | claimed |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | claimed |
| US-12194109-B2 | Radioactive compound for treatment of melanoma and use thereof | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2025-01-14 | — | — | US | disclosed |
| EP-3816156-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2021-05-05 | — | — | EP | disclosed |
| US-20210113719-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2021-04-22 | — | — | US | disclosed |
| US-20210113719-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2021-04-22 | — | — | US | disclosed |
| CN-112601740-A | Radioactive compounds for the treatment of melanoma and uses thereof | 全南大学校产学协力团 | 2021-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12194109-B2 | Radioactive compound for treatment of melanoma and use thereof | CD47, TYR, NRAS | MAOB 1807/4885HIF1A 371/4885ALOX15 3201/4885 |
| US-20210113719-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | CD47, TYR, NRAS | MAOB 1807/4885HIF1A 371/4885ALOX15 3201/4885 |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | MAOB 3222/4885HIF1A 2401/4885ALOX15 3350/4885 |
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | MAOB 3222/4885HIF1A 2401/4885ALOX15 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.