Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916498 | 1.00 | KDM4E (0.49) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL24916335 | 0.99 | KDM4E (0.51) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL29923190 | 0.99 | KDM4E (0.51) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL29923662 | 0.90 | SMN1; SMN2 (0.48) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL24915662 | 0.90 | SMN1; SMN2 (0.48) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL24915852 | 0.89 | HTT (0.48) | KDM4ETP53HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29923685 | 0.89 | HTT (0.48) | KDM4ETP53HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL24916132 | 0.87 | KDM4E (0.42) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL24916141 | 0.87 | ALDH1A1 (0.40) | KDM4ETP53HTTSMN1; SMN2ALOX12 | |
| SCHEMBL29923354 | 0.87 | ALDH1A1 (0.40) | KDM4ETP53HTTSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |