Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17056146 | 1.00 | HPGD (0.46) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL16745258 | 0.93 | P2RY6 (0.42) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL30520076 | 0.88 | FTO (0.58) | HPGDTDP1ALDH1A1HSD17B10FTO | |
| SCHEMBL30595817 | 0.88 | FTO (0.58) | HPGDTDP1ALDH1A1HSD17B10FTO | |
| SCHEMBL15326935 | 0.88 | FTO (0.58) | HPGDTDP1ALDH1A1HSD17B10FTO | |
| SCHEMBL18270247 | 0.88 | CYP3A4 (0.48) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL23760042 | 0.87 | FTO (0.45) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL23977365 | 0.86 | KCNH2 (0.40) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL22600489 | 0.85 | KCNH2 (0.47) | HPGDTDP1ALDH1A1CYP3A4HIF1A | |
| SCHEMBL23509569 | 0.83 | KCNH2 (0.48) | HPGDTDP1ALDH1A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320073-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216616-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |