Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 8/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | NEK4 | P51957 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425260 | 1.00 | MTNR1B (0.49) | MTNR1BMTNR1AEGFRPDPK1PDGFRA | |
| SCHEMBL27947745 | 0.81 | MTNR1B (0.50) | MTNR1BMTNR1APDPK1PDGFRARAB9A | |
| SCHEMBL22766493 | 0.81 | MTNR1B (0.50) | MTNR1BMTNR1AEGFRPDPK1PDGFRA | |
| SCHEMBL3249749 | 0.79 | MTNR1B (0.52) | MTNR1BMTNR1AEGFRPDPK1PDGFRA | |
| SCHEMBL5265681 | 0.79 | MTNR1B (0.51) | MTNR1BMTNR1AMAP4K4NPC1RAB9A | |
| SCHEMBL24916492 | 0.77 | CYP1A1 (0.36) | MTNR1BMTNR1AEGFRPDGFRAMAP4K4 | |
| SCHEMBL29923631 | 0.77 | CYP1A1 (0.36) | MTNR1BMTNR1AEGFRPDGFRAMAP4K4 | |
| SCHEMBL21783691 | 0.77 | MTNR1B (0.51) | MTNR1BMTNR1AEGFRPDGFRADYRK3 | |
| SCHEMBL21783731 | 0.77 | MTNR1B (0.47) | MTNR1BMTNR1AEGFRPDPK1PDGFRA | |
| SCHEMBL14400285 | 0.77 | MTNR1B (0.64) | MTNR1BMTNR1ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |