Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916492 | 1.00 | CYP1A1 (0.36) | CYP1A1CYP1B1MTNR1BMTNR1APDGFRB | |
| SCHEMBL29923616 | 0.77 | MTNR1B (0.49) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL425260 | 0.77 | MTNR1B (0.49) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL24916495 | 0.77 | PSMB5 (0.35) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL29923786 | 0.77 | PSMB5 (0.35) | MTNR1BMTNR1APDGFRBPDGFRAALDH1A1 | |
| SCHEMBL24916019 | 0.76 | CYP1A1 (0.34) | CYP1A1CYP1B1MTNR1BMTNR1APDGFRB | |
| SCHEMBL18807619 | 0.76 | CYP1A2 (0.38) | CYP1A2KDM4E | |
| SCHEMBL24916128 | 0.71 | MAPT (0.34) | MAPT | |
| SCHEMBL29923857 | 0.71 | MAPT (0.34) | MAPT | |
| SCHEMBL27192288 | 0.71 | CYP11B1 (0.51) | CYP1A2CYP3A4CYP2C19EGFRCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |