Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27204876 | 1.00 | PARP1 (0.33) | PARP1SMN1; SMN2FKBP1ADRD2HSD11B1 | |
| SCHEMBL27172709 | 1.00 | PARP1 (0.33) | PARP1SMN1; SMN2FKBP1ADRD2HSD11B1 | |
| SCHEMBL29923808 | 0.94 | PARP1 (0.33) | PARP1SMN1; SMN2FKBP1ADRD2HSD11B1 | |
| SCHEMBL27167401 | 0.81 | DRD2 (0.32) | SMN1; SMN2DRD2HSD11B1MEN1KMT2A | |
| SCHEMBL27167396 | 0.80 | PARP1 (0.34) | PARP1SMN1; SMN2FKBP1ADRD2MEN1 | |
| SCHEMBL30053807 | 0.80 | PARP1 (0.34) | PARP1SMN1; SMN2FKBP1ADRD2MEN1 | |
| SCHEMBL24916114 | 0.77 | SMN1; SMN2 (0.36) | PARP1SMN1; SMN2FKBP1AMEN1KMT2A | |
| SCHEMBL29923353 | 0.77 | SMN1; SMN2 (0.36) | PARP1SMN1; SMN2FKBP1AMEN1KMT2A | |
| SCHEMBL30054324 | 0.76 | MEN1 (0.32) | PARP1SMN1; SMN2DRD2MEN1KMT2A | |
| SCHEMBL24915789 | 0.75 | WDR5 (0.45) | SMN1; SMN2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |