Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6159628 | 0.75 | NUDT1 (0.51) | MAPTKDM4EMAPK1NPSR1NUDT1 | |
| SCHEMBL1223537 | 0.75 | MTNR1B (0.43) | MAPTNPSR1NCF1NPC1ALDH1A1 | |
| SCHEMBL6159581 | 0.72 | NUDT1 (0.63) | MAPTNUDT1GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL6162260 | 0.71 | NUDT1 (0.61) | MAPTNUDT1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5288680 | 0.71 | PDE10A (0.53) | MAPTMAPK1ADRA1DADRA1AADRA1B | |
| SCHEMBL30296979 | 0.71 | DRD1 (0.56) | MAPTKDM4EDRD1DRD5LMNA | |
| SCHEMBL27806895 | 0.71 | DRD1 (0.56) | MAPTKDM4EDRD1DRD5LMNA | |
| SCHEMBL27946081 | 0.70 | MAPT (0.75) | MAPTKDM4EMAPK1NPSR1DRD1 | |
| SCHEMBL10536109 | 0.70 | MAPT (0.62) | MAPTKDM4EMAPK1NPSR1DRD1 | |
| SCHEMBL29978754 | 0.70 | MAPT (0.62) | MAPTKDM4EMAPK1NPSR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |