Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.61 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CHKA | P35790 | 2/20 | 0.50 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.47 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365024 | 1.00 | NR4A2 (0.61) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL317202 | 0.79 | NR4A2 (0.66) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL29396540 | 0.79 | NR4A2 (0.66) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL18544879 | 0.79 | GAK (0.44) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL4744073 | 0.79 | HTT (0.51) | NR4A2SOS2CYP1A2KMT2AGAA | |
| Bromide SCHEMBL1611915 | 0.78 | NR4A2 (0.63) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11519956 | 0.78 | NR4A2 (0.63) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| Bromide SCHEMBL1611919 | 0.78 | NR4A2 (0.63) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| Iodide SCHEMBL11565912 | 0.78 | GAK (0.43) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL20427414 | 0.76 | HTR1A (0.54) | NR4A2SOS2CYP1A2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |