Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | BMP4 | P12644 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365024 | 0.79 | NR4A2 (0.61) | GAANR4A2SOS2PRNPKMT2A | |
| SCHEMBL29923701 | 0.79 | NR4A2 (0.61) | GAANR4A2SOS2PRNPKMT2A | |
| SCHEMBL3842625 | 0.78 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL7461823 | 0.73 | APP (0.58) | GAAAPPSMN1; SMN2 | |
| SCHEMBL7501744 | 0.73 | CYP1A2 (0.65) | HTTHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL13496183 | 0.72 | PKM (0.66) | HTTAPPHTR1AADRA1DADRA1A | |
| SCHEMBL21121632 | 0.70 | MAPT (0.69) | HTTGAAAPPNR4A2HTR1A | |
| SCHEMBL1702115 | 0.70 | LMNA (0.61) | GAANR4A2SOS2PRNPPOLB | |
| SCHEMBL8499187 | 0.69 | OPRM1 (0.53) | HTTGAAAPPHTR1AADRA1D | |
| SCHEMBL1690991 | 0.69 | IDO1 (0.58) | APPSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080201095-A1 | Method for Calibrating an Analytical Instrument | VERMILLION, INC. | 2008-08-21 | — | — | US | disclosed |
| WO-2008100941-A2 | A METHOD FOR CALIBRATING AN ANALYTICAL INSTRUMENT | CORRELOGIC SYSTEMS INC. (US) | 2008-08-21 | — | — | WO | disclosed |