Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923425 | 0.83 | L3MBTL1 (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL1223959 | 0.80 | POLB (0.52) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27167323 | 0.75 | GPR35 (0.30) | LMNA | |
| SCHEMBL9909176 | 0.72 | GAA (0.38) | ALDH1A1KDM4EHPGDMAPTRXFP1 | |
| SCHEMBL24915777 | 0.72 | MAPT (0.42) | POLBCRHR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29134970 | 0.71 | EPAS1 (0.43) | POLBKDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL13209743 | 0.70 | CYP1A2 (0.47) | POLBKDM4EHSD17B10MAPTLMNA | |
| SCHEMBL26632748 | 0.70 | MAPT (0.46) | POLBALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL19616463 | 0.70 | MAOB (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2CA1 | |
| SCHEMBL30064839 | 0.70 | MAOB (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |