Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923816 | 0.86 | EGLN1 (0.54) | EGLN1KDM4EL3MBTL1TET3TET2 | |
| SCHEMBL29923470 | 0.83 | EGLN1 (0.51) | EGLN1KDM4EL3MBTL1TET3TET2 | |
| SCHEMBL24916001 | 0.81 | HTT (0.44) | EGLN1AOX1KDM4ESLC40A1RAD52 | |
| SCHEMBL29923860 | 0.81 | PARP1 (0.49) | EGLN1 | |
| SCHEMBL29923738 | 0.80 | KMT2A (0.51) | EGLN1KDM4ESMN1; SMN2 | |
| SCHEMBL29923336 | 0.80 | EGLN1 (0.52) | EGLN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29923702 | 0.78 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL7026713 | 0.77 | AOX1 (0.76) | AOX1KDM4ERAD52ALDH1A1HSD17B10 | |
| SCHEMBL29923352 | 0.77 | EGLN1 (0.45) | EGLN1 | |
| SCHEMBL29923343 | 0.77 | PARP1 (0.52) | EGLN1KDM4EL3MBTL1TET3TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |