Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200021 | 0.86 | ALDH1A1 (0.44) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL13954896 | 0.81 | DRD2 (0.44) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL8526291 | 0.76 | HTR2A (0.41) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL4218125 | 0.75 | SMYD3 (0.52) | — | |
| SCHEMBL29923827 | 0.73 | DRD2 (0.40) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL8529795 | 0.72 | DRD2 (0.52) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL1682109 | 0.72 | KDM4E (0.54) | DRD2DRD4ALDH1A1MAPTACHE | |
| SCHEMBL28864425 | 0.71 | — | — | |
| SCHEMBL23384782 | 0.70 | ALDH1A1 (0.53) | DRD2DRD4ALDH1A1MAPTAR | |
| SCHEMBL8652483 | 0.70 | DRD2 (0.55) | DRD2DRD4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724066-B | Dihalogen impurity in ziprasidone hydrochloride intermediate and preparation method thereof | 海南鑫开源医药科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-112724066-B | Dihalogen impurity in ziprasidone hydrochloride intermediate and preparation method thereof | 海南鑫开源医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |