Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.81 |
| ▸ | MEN1 | O00255 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.80 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | MAOA | P21397 | 2/20 | 0.74 |
| ▸ | MAOB | P27338 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926782 | 1.00 | KMT2A (0.81) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL4970562 | 0.86 | MAOB (0.82) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL4971130 | 0.85 | MAOB (1.00) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL12501713 | 0.84 | KMT2A (0.78) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL5826076 | 0.84 | KMT2A (0.75) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL8647533 | 0.81 | KMT2A (0.70) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL4970371 | 0.81 | MAOB (1.00) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL28639941 | 0.80 | KMT2A (0.69) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL29923968 | 0.80 | KMT2A (0.69) | KMT2AMEN1MAPTPOLBRXFP1 | |
| SCHEMBL8642632 | 0.80 | MAOA (0.71) | KMT2AMEN1MAPTPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549043-B | Flavonoid tankyrase 2 inhibitor and preparation method and application thereof | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |