Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.82 |
| ▸ | MAOA | P21397 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | NPC1 | O15118 | 4/20 | 0.80 |
| ▸ | RAB9A | P51151 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.67 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.67 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971130 | 0.90 | MAOB (1.00) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL30643076 | 0.88 | RXFP1 (0.82) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL29923932 | 0.86 | KMT2A (0.81) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL28926782 | 0.86 | KMT2A (0.81) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL5826076 | 0.85 | KMT2A (0.75) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL12501713 | 0.85 | KMT2A (0.78) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL4970371 | 0.85 | MAOB (1.00) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL8642632 | 0.84 | MAOA (0.71) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL8647533 | 0.82 | KMT2A (0.70) | MAOBMAOAKMT2AMEN1NPC1 | |
| SCHEMBL8645195 | 0.81 | LMNA (0.67) | MAOBMAOAKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104925-A1 | CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES | UNIVERSIDADE DO PORTO (PT) | 2008-09-04 | — | — | WO | claimed |
| CN-109641864-B | Anti-infective agents | 邓迪大学 | 2023-04-04 | — | — | CN | disclosed |
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-27 | — | — | US | disclosed |
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-07-05 | — | — | US | disclosed |
| US-9861596-B2 | Compositions and methods for treating neurological diseases or injury | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2018-01-09 | — | — | US | disclosed |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2015-11-12 | — | — | US | disclosed |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2015-11-12 | — | — | US | disclosed |
| WO-2014074976-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-2014074976-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-2008104925-A1 | CHROMONE DERIVATIVES FOR USE AS ANTIOXIDANTS/PRESERVATIVES | UNIVERSIDADE DO PORTO (PT) | 2008-09-04 | — | — | WO | disclosed |
| EP-0787723-B1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-5843988-A | Cyclopropachromencarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0787723-A1 | CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES | SUNTORY LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10391070-B2 | Compositions and methods for treating neurological diseases or injury | PROC, GLS, NLN | MAOB 1041/4885MAOA 1292/4885KMT2A 1760/4885 |
| US-20150320702-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | PROC, GLS, NLN | MAOB 1041/4885MAOA 1292/4885KMT2A 1760/4885 |
| US-20180185306-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISEASES OR INJURY | PROC, GLS, NLN | MAOB 1041/4885MAOA 1292/4885KMT2A 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.