Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915959 | 0.79 | LRRK2 (0.45) | HTR1A | |
| SCHEMBL3555203 | 0.78 | HTR2A (0.62) | HTR1A | |
| SCHEMBL13437110 | 0.75 | HTR1A (0.56) | HTR1A | |
| SCHEMBL3924932 | 0.74 | HTR1A (0.58) | HTR1AALDH1A1 | |
| SCHEMBL3556367 | 0.73 | HTR1A (0.77) | HTR1A | |
| SCHEMBL3557770 | 0.73 | HTR1A (1.00) | HTR1A | |
| SCHEMBL3559471 | 0.72 | HTR1A (1.00) | HTR1A | |
| SCHEMBL24916404 | 0.72 | HTR1A (0.37) | HTR1AKMT2A | |
| SCHEMBL3564313 | 0.71 | HTR1A (1.00) | HTR1A | |
| SCHEMBL3563964 | 0.71 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |