Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915958 | 0.84 | ELANE (0.43) | LRRK2ELANEHTR1A | |
| SCHEMBL24916404 | 0.83 | HTR1A (0.37) | LRRK2ELANEHTR1ASOS1 | |
| SCHEMBL24915839 | 0.81 | LRRK2 (0.39) | LRRK2ELANE | |
| SCHEMBL24915957 | 0.80 | LRRK2 (0.45) | LRRK2HTR1AKRASSOS1 | |
| SCHEMBL29923937 | 0.79 | HTR1A (0.57) | HTR1A | |
| SCHEMBL24915954 | 0.79 | PRKDC (0.46) | LRRK2HTR1AATRATRIP | |
| SCHEMBL24915981 | 0.78 | HTR1A (0.38) | ELANEHTR1A | |
| SCHEMBL24915985 | 0.73 | HTR1A (0.42) | HTR1AKRASSOS1 | |
| SCHEMBL24915645 | 0.70 | NSD2 (0.44) | — | |
| SCHEMBL24916219 | 0.70 | PDE10A (0.41) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230026466-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR3 | LRRK2 560/4885ELANE 4095/4885HTR1A 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.