SCHEMBL29924205

SCHEMBL29924205

O=C1CCc2ccc(-c3ccccc3Cl)cc2N1CCN1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPK1 P28482 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
DRD2 P14416 6/20 0.45
DRD4 P21917 6/20 0.45
DRD3 P35462 6/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CHRM5 P08912 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
ADRB2 P07550 1/20 0.42
ADRB1 P08588 1/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901300 1.00 USP2 (0.46) USP2CYP1A2CYP3A4CYP2D6MAPK1
SCHEMBL28901360 0.85 SIGMAR1 (0.47) DRD2DRD4DRD3KDM4EADRA1B
SCHEMBL29924454 0.85 SIGMAR1 (0.47) DRD2DRD4DRD3KDM4EADRA1B
SCHEMBL29924292 0.85 DRD2 (0.52) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL29924191 0.85 DRD2 (0.52) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL28901320 0.85 DRD2 (0.52) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL28901318 0.85 DRD2 (0.52) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL29924503 0.84 DRD2 (0.43) DRD2DRD4DRD3KDM4EMAPT
SCHEMBL28901291 0.84 CYP1A2 (0.48) USP2CYP1A2CYP3A4CYP2D6CLK4
SCHEMBL28901294 0.83 DRD2 (0.50) DRD2DRD4DRD3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN claimed
CN-115073370-B Novel alkylaminos or salts, isomers, preparation method and application thereof 成都硕德药业有限公司 2024-12-17 CN disclosed
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN disclosed