Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149830 | 1.00 | ACSS2 (0.44) | ACSS2KDM4EGLP1RDRD2TBXA2R | |
| SCHEMBL30798065 | 0.91 | ACSS2 (0.42) | ACSS2KDM4EGLP1RDRD2TBXA2R | |
| SCHEMBL23363441 | 0.87 | ACSS2 (0.44) | ACSS2KDM4EDRD2TBXA2RIDH1 | |
| SCHEMBL29664315 | 0.87 | ACSS2 (0.44) | ACSS2KDM4EDRD2TBXA2RIDH1 | |
| SCHEMBL29555279 | 0.86 | ACSS2 (0.44) | ACSS2KDM4EDRD2TBXA2RIDH1 | |
| SCHEMBL25340969 | 0.86 | ACSS2 (0.44) | ACSS2KDM4EDRD2TBXA2RIDH1 | |
| SCHEMBL25340079 | 0.85 | ACSS2 (0.43) | ACSS2KDM4EGLP1RDRD2TBXA2R | |
| SCHEMBL29946034 | 0.85 | ACSS2 (0.43) | ACSS2KDM4EGLP1RDRD2TBXA2R | |
| SCHEMBL25322110 | 0.84 | ACSS2 (0.42) | ACSS2KDM4EDRD2TBXA2RIDH1 | |
| SCHEMBL30269530 | 0.84 | ACSS2 (0.42) | ACSS2KDM4EDRD2TBXA2RIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |