Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 8/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149862 | 1.00 | HTR2C (0.44) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29924682 | 1.00 | HTR2C (0.44) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29149939 | 0.88 | HTR2C (0.47) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29924313 | 0.88 | HTR2C (0.47) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29149805 | 0.86 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29924779 | 0.86 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29149807 | 0.86 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29924324 | 0.86 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29149819 | 0.86 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL29149767 | 0.86 | HTR2C (0.43) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |