Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150166 | 1.00 | LMNA (0.44) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL24186455 | 0.90 | LMNA (0.42) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL30286859 | 0.90 | LMNA (0.42) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL23980856 | 0.88 | RAB9A (0.45) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL30217421 | 0.88 | RAB9A (0.45) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL29149852 | 0.85 | LMNA (0.49) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL29924275 | 0.85 | LMNA (0.49) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL30680755 | 0.84 | LMNA (0.46) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL29150061 | 0.84 | LMNA (0.46) | LMNAMAPTRAB9AALDH1A1KMT2A | |
| SCHEMBL29149922 | 0.82 | KMT2A (0.43) | LMNAMAPTRAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |