Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30209267 | 1.00 | KDM4C (0.37) | KDM4CKDM4EPIK3R1PIK3CATBXAS1 | |
| SCHEMBL31025680 | 0.88 | ALDH1A1 (0.37) | KDM4EALDH1A1RAB9AABL1SLC2A1 | |
| SCHEMBL30209319 | 0.84 | KDM4E (0.37) | KDM4CKDM4EPIK3CATBXAS1ALDH1A1 | |
| SCHEMBL29924505 | 0.80 | KDM4C (0.37) | KDM4CKDM4ETBXAS1ALDH1A1RAB9A | |
| SCHEMBL27143674 | 0.80 | KDM4C (0.37) | KDM4CKDM4ETBXAS1ALDH1A1RAB9A | |
| SCHEMBL29586588 | 0.76 | KDM4C (0.38) | KDM4CKDM4EALDH1A1GRIN2BMAPT | |
| SCHEMBL30237710 | 0.75 | KDM4C (0.44) | KDM4CKDM4EALDH1A1RAB9ATEK | |
| SCHEMBL26611552 | 0.75 | PIK3R1 (0.34) | KDM4CKDM4EPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL26611555 | 0.75 | PIK3R1 (0.34) | KDM4CKDM4EPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL23361781 | 0.72 | FGFR1 (0.47) | KDM4CGRIN2BPTGER4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |