Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 12/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26611555 | 1.00 | PIK3R1 (0.34) | PIK3R1PIK3CAPTGER4GLP1RKDM4C | |
| SCHEMBL24575433 | 0.89 | ALDH1A1 (0.36) | KDM4EALDH1A1CASP1HSD17B10GAA | |
| SCHEMBL24575434 | 0.89 | ALDH1A1 (0.36) | KDM4EALDH1A1CASP1HSD17B10GAA | |
| SCHEMBL30209293 | 0.85 | FEN1 (0.37) | KDM4EALDH1A1CASP1HSD17B10GAA | |
| SCHEMBL26611050 | 0.81 | PTGER4 (0.34) | PTGER4GLP1RKDM4CCTSDKDM4E | |
| SCHEMBL25291477 | 0.81 | PTGER4 (0.34) | PTGER4GLP1RKDM4CCTSDKDM4E | |
| SCHEMBL30209267 | 0.75 | KDM4C (0.37) | PIK3R1PIK3CAPTGER4KDM4CKDM4E | |
| SCHEMBL29924490 | 0.75 | KDM4C (0.37) | PIK3R1PIK3CAPTGER4KDM4CKDM4E | |
| SCHEMBL25366110 | 0.74 | PTGER4 (0.55) | PTGER4GLP1RKDM4C | |
| SCHEMBL20266409 | 0.74 | GLP1R (0.50) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124470-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-04-18 | — | — | US | disclosed |
| EP-4269399-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022135572-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124470-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | SLC5A1, SLC5A2, CYP11B2 | PIK3R1 4290/4885PIK3CA 2352/4885PTGER4 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.